| ORIGINAL RESEARCH |
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| Year : 2019 | Volume
: 8
| Issue : 4 | Page : 178-182 |
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Modulation of cardiac autonomic tone in healthy neonates
Sumeet Tripathi1, Ekta Khandelwal2, Onkar Khandwal3
1 Associate Professor, Department of Physiology, Pt.J.N.M.Medical College, Raipur, Chhattisgarh, India
2 Associate Professor, Department of Physiology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
3 Professor, Department of Pediatrics, Pt.J.N.M. Medical College, Raipur, Chhattisgarh, India
Correspondence Address:
Ekta Khandelwal
Room No.3119, 3 rdfloor,3rdFloor, Department of Physiology, Gate No 5, AIIMS, Tatibandh, Raipur (C.G) 492001
India
 Source of Support: None, Conflict of Interest: None
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Cardiac autonomic tone is beat to beat fluctuation in heart rate. There is paucity of data on normal values of HRV in newborn infants. This study was an initiative to assess the feasibility of measurement and analysis of short term HRV in healthy term neonates. 20 healthy term neonates admitted in Neonatal Unit of Dr BRAM Hospital at Raipur, Chhattisgarh, who met the inclusion criteria of gestational age > 37 weeks & APGAR score >= 8 at 5minutes were included. Cardiac autonomic modulation was assessed by short term heart rate variability by 5 minutes continuous recording of ECG using a lead ? electrocardiogram (ECG). The analysis of HRV was done by Time domain, Frequency domain and Non Linear methods. Time Domain values were expressed in first quartile and third quartile of SDSD were between (10.78 – 36.43ms), RMSSD were (10.82 - 36.4) ms andpRR50 and (0.39 - 16.82). Frequency domain values expressed in first quartile and third quartile of LF were (56.04 – 72.97 n.u.), HF were (26.76 – 41.58 n.u). Value of the LF/HF ratio is (1.33- 2.72). Non linear values expressed in first quartile and third quartile of SD1 were between (7.62 – 25.76 ms) & SD2 were ( 25.50-46.03 ms). This study showed recording of heart rate variability in neonates is feasible. It can be a promising noninvasive diagnostic and prognostic tool in the assessment of neonatal and infant diseases.
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